Detlef Neumann and Diana Boraschi* Hannover Medical School, Hannover, Germany Institute of Biomedical Technologies, CNR, Pisa, Italy __________________________________________________________________________________ *Correspondence: Diana Boraschi, Laboratory of Cytokines, Unit of Immunobiology, Institute of Biomedical Technologies, Area della Ricerca di S. Cataldo, Via G. Moruzzi 1, I-56124 Pi...

BACKGROUND To report the nonrandomized first-in-human phase I trial of PRS-050, a novel, rationally engineered Anticalin based on human tear lipocalin that targets and antagonizes vascular endothelial growth factor A (VEGF-A). METHODS Patients with advanced solid tumors received PRS-050 at 0.1 mg/kg to 10 mg/kg by IV in successive dosing cohorts according to the 3+3 escalation scheme. The pri...

The distinction between rules and similarity is central to our understanding of much of cognitive psychology. Two aspects of existing research have motivated the present work. First, in different cognitive psychology areas we typically see different conceptions of rules and similarity; for example, rules in language appear to be of a different kind compared to rules in categorization. Second, r...

*Correspondence: Dr. Giuseppe Rainaldi, Laboratory of Gene and Molecular Therapy, Institute of Clinical Physiology, CNR, Area della Ricerca, Via Moruzzi,1, 56124 Pisa, Italy; FAX: +39 050 3153327; Tel: +39 050 3153108; E-mail: [email protected]

doi: 10.9755/ejfa.2015-04-050

The highest exclusive jet multiplicity studied at LEP experiments is five. In this paper we compute the next-to-leading order QCD corrections to e + e ‐ annihilation to five jets, essentially closing the (pure) perturbative QCD studies of exclusive jetty final states at LEP. We compare fixed-order perturbative results with ALEPH data. We estimate hadronization corrections to five-jet observable...

La investigación tuvo como objetivo determinar la eficacia del programa educativo Profesor sin límites para desarrollar competencias digitales en docentes de educación secundaria. El estudio es enfoque cuantitativo, y se utilizó el diseño cuasi experimental. muestra lo conformaron 30 grupo experimental otros control, los pertenecen a instituciones educativas públicas distrito Junín, Perú. Los r...

Six women with normal menstrual cycles were treated over six cycles with Fysioquens, a normophasic contraceptive consisting of 7 tablets of ethinyloestradiol (EE) 0-050 mg and 15 tablets containing 1-0 mg lynestrenol + 0-050 mg EE. In the 1st, 3rd and 6th treatment cycles and in the cycles before and after treatment, hormonal assays and other tests were carried out to determine whether ovulatio...